D-dimer

Compartilhe esta página
Imprimir este artigo
Esta página foi útil?
Também chamado: Fragment D-dimer; Fibrin degradation fragment
Nome formal: D-dimer
Exames relacionados: Fibrin Degradation Products (FDP); Prothrombin Time (PT); Partial Thromboplastin Time (PTT); Fibrinogen; Platelet Count

De relance

Por que fazer este exame?

To help diagnose or rule out thrombotic (blood clot-producing) diseases and conditions

Quando fazer este exame?

When you have symptoms of a disease or condition that causes acute and/or chronic inappropriate blood clot formation such as: DVT (Deep Vein Thrombosis), PE (Pulmonary Embolism), or DIC (Disseminated Intravascular Coagulation), and to monitor the progress and treatment of DIC and other thrombotic conditions

Amostra:

A blood sample drawn from a vein in your arm or sometimes from a fingerstick (a blood sample drawn from the fingertip)

A amostra

O que está sendo pesquisado?

When a vein or artery is injured and begins to leak blood, a sequence of clotting steps and factors (called the coagulation cascade) is activated by the body to limit the bleeding and create a blood clot to plug the hole.  During this process, threads of a protein called fibrin are produced.  These threads are crosslinked (glued together) to form a fibrin net that catches platelets and helps hold the forming blood clot together at the site of the injury.

Once the area has had time to heal, the body uses a protein called plasmin to break the clot (thrombus) into small pieces so that it can be removed.  The fragments of the disintegrating fibrin in the clot are called fibrin degradation products (FDP).  One of the FDPs produced is D-dimer, which consists of variously sized pieces of crosslinked fibrin.  D-dimer is normally undetectable in the blood and is produced only after a clot has formed and is in the process of being broken down. Measurement of D-dimer can tell your doctor that something has increased above normal the body's clotting mechanisms.

Como a amostra é obtida para o exame?

Typically, a blood sample is drawn from a vein in your arm. As an alternative, particularly in pediatric care, the blood sample is drawn from the fingertip.

NOTA: Se exames médicos em você ou em alguém importante para você o deixam ansioso ou constrangido, ou se você tem dificuldade de lidar com eles, leia um ou mais dos seguintes artigos: Lidando com dor, desconforto ou ansiedade durante o exame, Conselhos sobre exames de sangue, Conselhos para ajudar crianças durante exames médicos, and Conselhos para ajudar idosos durante exames médicos.

Outro artigo, Siga essa amostra, fornece uma visão da coleta e do processamento de uma amostra de sangue e de uma amostra de cultura da garganta.

O exame

Perguntas frequentes

Pergunte ao laboratório

* indica um campo necessário



Por favor, indique se você é:   
  
  



Você deve fornecer um endereço de e-mail válido para receber uma resposta.



| |

Fontes do artigo

« Voltar para páginas relacionadas

NOTA: Este artigo se baseia em pesquisas que incluíram as fontes citadas e a experiência coletiva de Lab Tests Online Conselho de Revisão Editorial. Este artigo é submetido a revisões periódicas do Conselho Editorial, e pode ser atualizado como resultado dessas revisões. Novas fontes citadas serão adicionadas à lista e distinguidas das fontes originais usadas.

S1
Thomas, Clayton L., Editor (1997). Taber’s Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

S2
Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby’s Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

S3
Disseminated Intravascular Coagulation Panel. AACC View Q&A [On-line information]. Available FTP: http://www.aacc.org/access/outcomes/18_disseminated_intravascular.stm

S4
(2003 January). In Search of a Killer - Does D-dimer Help? American College of Emergency Physicians [On-line information]. Available FTP: http://www.acep.org/1,32394,0.html

S5
(2001 July 17). Improving the Diagnosis of Pulmonary Embolism in the Emergency Department. Annals of Internal Medicine v135 (2) [On-line Journal]. Available FTP: http://www.annals.org/issues/v135n2/nts/200107170-00005.html

S6
Strandness Jr., DE. Are Physical Findings Totally Useless In DVT/PE? Vascular Web, University of Washington School of Medicine [On-line information]. Available FTP: http://www.vascularweb.org/doc/54

S7
Tan, J. (2000 December). Clinical Applications of the D-Dimer Assay in Deep Venous Thrombosis. San Bernardino County Medical Society Bulletin [On-line newsletter]. Available FTP: http://www.sbcms.org/southcalphysician/2000/nov-dec/art5.htm

S8
Prazeres, G. Deep Vein Thrombosis - Part II. Internal Medicine MedStudents [On-line information]. Available FTP: http://www.medstudents.com.br/medint/medint5.htm

S9
D-Dimer: Lifting the Veil of Confusion. Diagnostics today Online, Beckman Coulter[On-line information]. Available online

S10
Began, T. (2002 October). Elisa D-Dimer: How Accurate For PE Diagnosis? PulmonaryReviews.com, vol 7 (10) [On-line information]. Available FTP: http://www.pulmonaryreviews.com/oct02/pr_oct02_ELISA.html

S11
Cortese Hassett, A. (2000 February). D-dimer Testing and Acute Venous Thromboembolism. Transfusion Medicine Update, The Institute for Transfusion Medicine [On-line information]. Available FTP: http://www.itxm.org/TMU2000/tmu2-2000.htm

S12
Titus, K. (2003 January). Identity crisis persists—which D-dimer? CAP Today, In the News [On-line Journal. Available FTP: http://www.cap.org/captoday/archive/2003/0103/DdimerCover.html

S13
Cruickshank, M. (2001 January). Practical Treatment Guidelines, Suspected DVT. The Thrombosis Interest Group of Canada [On-line information]. Available FTP: http://www.tigc.org/eguidelines/suspdvt.htm

S14
Abumuhor, I. and Hope Kearns, E.(2002 April 26). Thrombotic Thrombocytopenic Purpura, Differential Diagnosis. The Virtual Health Care Team [On-line information]. Available FTP: http://www.vhct.org/case2300/diagnosis.shtml

S15
Venous Thromboembolism (VTE), Qualitative (Time Sensitive). ARUP's Guide to Clinical Laboratory Testing (CLT) [On-line information]. Available FTP: http://www.aruplab.com/guides/clt/tests/clt_250b.htm

S16
Yen, S. (2001 March 27). D-Dimer For The Diagnosis Of Deep Vein Thrombosis. Internal Medicine Evidence Based Medicine Newsletter, Edition 8 [On-line Newsletter]. Available FTP: http://www.wshmc.org/wshcresidency/EBMNL/EBMNL032701.htm